The DDR1 antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD167, DDR, and DDR1. This antibody recognizes Human antigen. The DDR1 antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Mouse monoclonal DDR1 antibody
DDR1 is a Receptor Tyrosine Kinase that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain